What I was wondering

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Re: What I was wondering

Postby somnonaut » Thu Jul 30, 2015 2:00 pm

Interesting....could be way o implement z-ratio as an Alzheimers sleep marker since it measures depth of sleep from a single channel and yields quantified metric that then can be used in further numeric manipulations including a slope to the total recording depicting the "overall trend" of the sleep. And as we know, a typical healthy person sleeps with more SWS (deep) early in the recording and more REM (light) later in the recording. So having a metric of the depth of sleep depicts this numerically, easily and transparently.
http://www.z-eeg.com
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Re: What I was wondering

Postby labman2 » Thu Jul 30, 2015 2:40 pm

somnonaut wrote:Interesting....could be way o implement z-ratio as an Alzheimers sleep marker since it measures depth of sleep from a single channel and yields quantified metric that then can be used in further numeric manipulations including a slope to the total recording depicting the "overall trend" of the sleep. And as we know, a typical healthy person sleeps with more SWS (deep) early in the recording and more REM (light) later in the recording. So having a metric of the depth of sleep depicts this numerically, easily and transparently.
http://www.z-eeg.com



could be helpful.... why not shoot them an email amd see if they are interested! It makes sense to me!

Brendan
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Re: What I was wondering

Postby somnonaut » Fri Jul 31, 2015 1:14 am

z-Ratio's next step can be either creation of a box to piggyback PSG (use two inputs of PSG) and provide bluetooth computer for separate z-ratio slice of desktop showing channel, z-ratio trend and other parameters in a cordoned off piece of desktop real estate so that any other software running would have this at the top edge of their screen. This will provide any lab with an imediate entre into z-ratio world, and its metrics.

OR

phenotype overnight z-ratio trends through mass accumulation of tracings showing varied diagnoses with their z-ratio signature. If there is a PSG signature...there will be a z-ratio signature.
See http://www.sleep-wake.com/z-ratio_presentation.pps especially slides 3, 8, 22, 28, 33 thru 38
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Re: What I was wondering

Postby labman2 » Fri Apr 22, 2016 5:40 pm

http://www.sleepreviewmag.com/2016/04/g ... ment-79773



Years ago on binarysleep.com I started this thread and I and others pondered wether there was a connection! My mom died of Alzheimers and also had bad sleep apnea and I felt strongly that the constant assaults on the brain during these apneic events led to Alzheimers! Seems like my tech pals who chimed in on that thread were many years ahead of the research :) Check out our binarysleep.com thread of info on the topic from back in 2008!
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Re: What I was wondering

Postby labman2 » Thu Apr 28, 2016 8:43 pm

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Re: What I was wondering

Postby labman2 » Sat Oct 15, 2016 3:49 am

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Re: What I was wondering

Postby labman2 » Thu Oct 05, 2017 2:56 am

The latest addition to our mounting evidence

http://capeandislands.org/post/brains-l ... s#stream/0
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Re: What I was wondering

Postby somnonaut » Fri Oct 06, 2017 4:28 am

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Re: What I was wondering

Postby labman2 » Fri Nov 10, 2017 8:26 pm

https://www.medscape.com/viewarticle/88 ... 212DY#vp_1

They are catching up to our thinking from 2008! :)
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Re: What I was wondering

Postby somnonaut » Tue Nov 28, 2017 3:56 pm

New Culprit in Alzheimer’s Disease Development Identified
http://neurosciencenews.com/bctf-alzhei ... tics-2283/
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Re: What I was wondering

Postby labman2 » Wed May 16, 2018 2:40 pm

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